cGMP Manufacturing

With our state-of-the-art cGMP production suites, we offer cGMP manufacturing services for both microbial and mammalian cell-based processes.

We are specialized in the production of therapeutic biologics such as recombinant proteins and monoclonal antibodies for pre-clinical and clinical supply. Our facilities are FDA and MHRA inspected.

Expression in Bacteria

  • Bacterial hosts such as E.coli, Bacillus
  • Expression screening in E.coli to identify suitable host strain and optimal conditions for expression
  • Scale of expression: 2 – 10 L lab scale and 20 – 225L pilot scale

Expression in Yeast

  • Hosts such as Saccharomyces sp. and Pichia pastoris
  • Expression screening to identify suitable host strain and optimal conditions for expression
  • Scale of expression: 2 – 10 L lab scale and 20 – 225 L pilot scale

Expression in Insect cells

  • Insect Cell Lines used: Sf9, Sf21, High Five
  • Generation of high titer recombinant baculovirus
  • MOI studies
  • Scale of expression: 2 to 50L in Wave Bioreactor

Expression in mammalian cells

  • Mammalian Cell lines: CHO-K1, HEK 293, CHO-S, CHO-DG44 etc.
  • Transient transfection for expression and purification of proteins
  • Generation of stable cell lines expressing recombinant proteins
  • Scale of expression: 2 – 10 L lab scale and 30 – 300 L pilot scale